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1

Overview of the FGF23-Klotho axis

Journal:

Pediatric Nephrology

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

2

Nuclear localization of Klotho in brain: an anti-aging protein

Dwight C. German, Ida Khobahy, Johanne Pastor, Makoto Kuro-o, Xinran Liu

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 2.21 MB

english, 2012

3

Molecular Regulation of Phosphate Metabolism by Fibroblast Growth Factor-23–Klotho System

Cheng, Chung-Yi, Kuro-o, Makoto, Razzaque, Mohammed S.

Journal:

Advances in Chronic Kidney Disease

Year:

2011

Language:

english

File:

PDF, 232 KB

english, 2011

4

PTH, vitamin D, and the FGF-23-klotho axis and heart: going beyond the confines of nephrology

Navarro-García, José Alberto, Fernández-Velasco, María, Delgado, Carmen, Delgado, Juan F., Kuro-o, Makoto, Ruilope, Luis Miguel, Ruiz-Hurtado, Gema

Journal:

European Journal of Clinical Investigation

Year:

2018

Language:

english

File:

PDF, 257 KB

english, 2018

5

Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model

Wang, Qin, Ishizawa, Kenichi, Li, Jinping, Fujii, Wataru, Nemoto, Yoshikazu, Yamazaki, Osamu, Tamura, Yoshifuru, Miura, Yutaka, Nie, Xuedan, Abe, Ryo, Segawa, Hiroko, Kuro-O, Makoto, Shibata, Shigeru

Journal:

Communications Biology

Year:

2020

File:

PDF, 3.13 MB

2020

6

Improvement of multiple pathophysiological phenotypes of klotho (kl/kl) mice by adenovirus-mediated expression of the klotho gene

Takako Shiraki-Iida, Akihiro Iida, Yoko Nabeshima, Hideharu Anazawa, Satoshi Nishikawa, Masaki Noda, Makoto Kuro-o, Yo-ichi Nabeshima

Journal:

The Journal of Gene Medicine

Year:

2000

Language:

english

File:

PDF, 604 KB

english, 2000

7

Ultra-short echo time (UTE) MR imaging of the lung: Comparison between normal and emphysematous lungs in mutant mice

Masaya Takahashi, Osamu Togao, Makoto Obara, Marc van Cauteren, Yoshiharu Ohno, Shigehiro Doi, Makoto Kuro-O, Craig Malloy, Connie C. Hsia, Ivan Dimitrov

Journal:

Journal of Magnetic Resonance Imaging

Year:

2010

Language:

english

File:

PDF, 350 KB

english, 2010

8

Improved protein arrays for quantitative systems analysis of the dynamics of signaling pathway interactions

Xiaoyu Wang, Ying Dong, Ameena J Jiwani, Yonglong Zou, Johanne Pastor, Makoto Kuro-o, Amyn A Habib, Minzi Ruan, David A Boothman, Chin-Rang Yang

Journal:

Proteome Science

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

9

Klothoinsufficiency causes decrease of ribosomal RNA gene transcription activity, cytoplasmic RNA and rough ER in the spinal anterior horn cells

Yorito Anamizu, Hiroshi Kawaguchi, Atsushi Seichi, Shinji Yamaguchi, Emiko Kawakami, Naotoshi Kanda, Shiro Matsubara, Makoto Kuro-o, Yoichi Nabeshima, Kozo Nakamura, Kiyomitsu Oyanagi

Journal:

Acta Neuropathologica

Year:

2005

Language:

english

File:

PDF, 664 KB

english, 2005

10

Accelerated suicidal erythrocyte death in Klotho-deficient mice

Daniela S. Kempe, Teresa F. Ackermann, Stephanie S. Fischer, Saisudha Koka, Krishna M. Boini, Hasan Mahmud, Michael Föller, Kevin P. Rosenblatt, Makoto Kuro-o, Florian Lang

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 225 KB

english, 2009

11

Klotho

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 290 KB

english, 2010

12

Alteration in N-glycomics during mouse aging: a role for FUT8

Valerie Vanhooren, Sylviane Dewaele, Makoto Kuro-o, Naoyuki Taniguchi, Laurent Dollé, Leo A. van Grunsven, Evgenia Makrantonaki, Christos C. Zouboulis, Cuiying C. Chen, Claude Libert

Journal:

Year:

2011

Language:

english

File:

PDF, 527 KB

english, 2011

13

10.1038/36285

Kuro-o, Makoto, Nabeshima, Yo-ichi, Matsumura, Yutaka, Aizawa, Hiroki, Kawaguchi, Hiroshi, Suga, Tatsuo, Utsugi, Toshihiro, Ohyama, Yoshio, Kurabayashi, Masahiko, Kaname, Tadashi, Kume, Eisuke, Iwasak

Journal:

Year:

1997

Language:

english

File:

PDF, 594 KB

english, 1997

14

Diversity and variability of smooth muscle phenotypes of renal arterioles as revealed by myosin isoform expression

Kimura, Kenjiro, Nagai, Ryozo, Sakai, Tatsuo, Aikawa, Masanori, Kuro-o, Makoto, Kobayashi, Naoto, Shirato, Isao, Inagami, Tadashi, Oshi, Masaya, Suzuki, Naoe

Journal:

Kidney International

Year:

1995

Language:

english

File:

PDF, 1.44 MB

english, 1995

15

Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice

Ferenc Izbeki, David T. Asuzu, Andrea Lorincz, Michael R. Bardsley, Laura N. Popko, Kyoung Moo Choi, David L. Young, Yujiro Hayashi, David R. Linden, Makoto Kuro-o, Gianrico Farrugia, Tamas Ordog

Journal:

The Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

16

Aromatase Deficiency Causes Altered Expression of Molecules Critical for Calcium Reabsorption in the Kidneys of Female Mice

Orhan K Öz, Asghar Hajibeigi, Kevin Howard, Carolyn L Cummins, Monique van Abel, Rene JM Bindels, R Ann Word, Makoto Kuro-o, Charles YC Pak, Joseph E Zerwekh

Journal:

Journal of Bone and Mineral Research

Year:

2007

Language:

english

File:

PDF, 4.58 MB

english, 2007

17

Klotho Variants and Chronic Hemodialysis Mortality

David J. Friedman, Maryam Afkarian, Hector Tamez, Ishir Bhan, Tamara Isakova, Myles Wolf, Elizabeth Ankers, Jun Ye, Marcello Tonelli, Carmine Zoccali, Makoto Kuro-o, Orson Moe, S. Ananth Karumanchi, R

Journal:

Journal of Bone and Mineral Research

Year:

2009

Language:

english

File:

PDF, 1.18 MB

english, 2009

18

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF19 and Cancer

Year:

2012

Language:

english

File:

PDF, 164 KB

english, 2012

19

UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells

Okuda, Akihiko, Fukushima, Akiko, Nishimoto, Masazumi, Orimo, Akira, Yamagishi, Toshiyuki, Nabeshima, Yoko, Kuro-o, Makoto, Nabeshima, Yo-ichi, Boon, Kathy, Keaveney, Marie

Journal:

The EMBO Journal

Year:

1998

Language:

english

File:

PDF, 653 KB

english, 1998

20

Endocrine fibroblast growth factors as regulators of metabolic homeostasis

Hiroshi Kurosu, Makoto Kuro-o

Journal:

Year:

2009

Language:

english

File:

PDF, 226 KB

english, 2009

21

Klotho is a substrate for α-, β- and γ-secretase

Laura Bloch, Olga Sineshchekova, Daniela Reichenbach, Karina Reiss, Paul Saftig, Makoto Kuro-o, Christoph Kaether

Journal:

Year:

2009

Language:

english

File:

PDF, 407 KB

english, 2009

22

Regulation of the Na+/K+ ATPase by Klotho

Mentor Sopjani, Ioana Alesutan, Miribane Dërmaku-Sopjani, Shuchen Gu, Christine Zelenak, Carlos Munoz, Ana Velic, Michael Föller, Kevin P. Rosenblatt, Makoto Kuro-o, Florian Lang

Journal:

Year:

2011

Language:

english

File:

PDF, 737 KB

english, 2011

23

Regulation of multiple ageing-like phenotypes by inducible klotho gene expression in klotho mutant mice

Hiroaki Masuda, Hirotaka Chikuda, Tatsuo Suga, Hiroshi Kawaguchi, Makoto Kuro-o

Journal:

Mechanisms of Ageing and Development

Year:

2005

Language:

english

File:

PDF, 870 KB

english, 2005

24

A potential link between phosphate and aging—Lessons from Klotho-deficient mice

Journal:

Mechanisms of Ageing and Development

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

25

Examination of smooth muscle cell lineage in arterial remodeling with smooth muscle specific marker: Smooth muscle myosin heavy chain

Hiroshi Iwata, Masataka Sata, Ichiro Manabe, Katsuhito Fujiu, Makoto Kuro-o, Ryozo Nagai

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

26

Role of Klotho in Aging, Phosphate Metabolism, and CKD

George B. John, Chung-Yi Cheng, Makoto Kuro-o

Journal:

American Journal of Kidney Diseases

Year:

2011

Language:

english

File:

PDF, 697 KB

english, 2011

27

Klotho gene delivery suppresses Nox2 expression and attenuates oxidative stress in rat aortic smooth muscle cells via the cAMP-PKA pathway

Yuhong Wang, Makoto Kuro-o, Zhongjie Sun

Journal:

Year:

2012

Language:

english

File:

PDF, 515 KB

english, 2012

28

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || Physiology of FGF15/19

Year:

2012

Language:

english

File:

PDF, 206 KB

english, 2012

29

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || Klotho and βKlotho

Year:

2012

Language:

english

File:

PDF, 276 KB

english, 2012

30

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || Understanding the Structure-Function Relationship between FGF19 and Its Mitogenic and Metabolic Activities

Year:

2012

Language:

english

File:

PDF, 415 KB

english, 2012

31

Isolation of the Embryonic Form of Smooth Muscle Myosin Heavy Chain (SMemb/NMHC-B) Gene and Characterization of Its 5′-Flanking Region

Ichiro Manabe, Masahiko Kurabayashi, Yukio Shimomura, Makoto Kuro-o, Noboru Watanabe, Masafumi Watanabe, Masanori Aikawa, Toru Suzuki, Yoshio Yazaki, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 1.58 MB

english, 1997

32

Identification of the HumanKlothoGene and Its Two Transcripts Encoding Membrane and SecretedKlothoProtein

Yutaka Matsumura, Hiroki Aizawa, Takako Shiraki-Iida, Ryozo Nagai, Makoto Kuro-o, Yo-ichi Nabeshima

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.19 MB

english, 1998

33

Klotho Protein Protects against Endothelial Dysfunction

Yuichiro Saito, Takahiro Yamagishi, Tetsuya Nakamura, Yoshio Ohyama, Hiroki Aizawa, Tatsuo Suga, Yutaka Matsumura, Hiroaki Masuda, Masahiko Kurabayashi, Makoto Kuro-o, Yo-ichi Nabeshima, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 122 KB

english, 1998

34

Molecular Cloning of RatklothocDNA: Markedly Decreased Expression ofklothoby Acute Inflammatory Stress

Yoshio Ohyama, Masahiko Kurabayashi, Hiroaki Masuda, Tetsuya Nakamura, Yasushi Aihara, Tadashi Kaname, Tatsuo Suga, Masashi Arai, Hiroki Aizawa, Yutaka Matsumura, Makoto Kuro-o, Yo-ichi Nabeshima, Ryo

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 1.35 MB

english, 1998

35

In Vivo klotho Gene Delivery Protects against Endothelial Dysfunction in Multiple Risk Factor Syndrome

Yuichiro Saito, Tetsuya Nakamura, Yoshio Ohyama, Toru Suzuki, Akihiro Iida, Takako Shiraki-Iida, Makoto Kuro-o, Yo-ichi Nabeshima, Masahiko Kurabayashi, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 157 KB

english, 2000

36

Identification of three types of PDGF-A chain gene transcripts in rabbit vascular smooth muscle and their regulated expression during development and by angiotensin II

Ken-ichi Nakahara, Hiroshi Nishimura, Makoto Kuro-o, Shun-ichi Takewaki, Misaki Iwase, Akiyuki Ohkubo, Yoshio Yazaki, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.31 MB

english, 1992

37

Vascular smooth muscle differentiation during development is associated with a decrease in PDGF-A chain gene expression

Ryozo Nagai, Ken-ichi Nakahara, Makoto Kuro-o, Hiroshi Nishimura, Masanori Aikawa

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1992

Language:

english

File:

PDF, 104 KB

english, 1992

38

Klotho and aging

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2009

Language:

english

File:

PDF, 564 KB

english, 2009

39

The Klotho gene family as a regulator of endocrine fibroblast growth factors

Hiroshi Kurosu, Makoto Kuro-o

Journal:

Molecular and Cellular Endocrinology

Year:

2009

Language:

english

File:

PDF, 316 KB

english, 2009

40

Endocrine FGFs and Klothos: emerging concepts

Journal:

Trends in Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 488 KB

english, 2008

41

Heterogeneity in smooth muscle cell population accumulating in the neointimas and the media of poststenotic dilatation of the rabbit carotid artery

Ei-ichi Okamoto, Kohji Imataka, Jun Fujii, Makoto Kuro-o, Ken-ichi Nakahara, Hiroshi Nishimura, Yoshio Yazaki, Ryozo Nagai

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.92 MB

english, 1992

42

Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

Takako Shiraki-Iida, Hiroki Aizawa, Yutaka Matsumura, Susumu Sekine, Akihiro Iida, Hideharu Anazawa, Ryozo Nagai, Makoto Kuro-o, Yo-ichi Nabeshima

Journal:

Year:

1998

Language:

english

File:

PDF, 273 KB

english, 1998

43

Activation of Na+-H+ Antiporter (NHE-1) gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system

Syin-ichi Takewaki, Makoto Kuro-o, Yukio Hiroi, Tsutomu Yamazaki, Tsuyoshi Noguchi, Akira Miyagishi, Ken-ichi Nakahara, Masanori Aikawa, Ichiro Manabe, Yoshio Yazaki, Ryozo Nagai

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1995

Language:

english

File:

PDF, 2.19 MB

english, 1995

44

Expression of Na+/Ca2+ exchanger (NCX1) gene in the developmental mouse embryo and adult mouse brain

Koji Wakimoto, Makoto Kuro-o, Noriyuki Yanaka, Issei Komuro, Yo-ichi Nabeshima, Yuji Imai

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2001

Language:

english

File:

PDF, 1.20 MB

english, 2001

45

Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes

Koji Wakimoto, Hisako Fujimura, Takahiro Iwamoto, Toru Oka, Kinji Kobayashi, Satomi Kita, Sumiyo Kudoh, Makoto Kuro-o, Yo-ichi Nabeshima, Munekazu Shigekawa, Yuji Imai, Issei Komuro

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.45 MB

english, 2003

46

Disease model: human aging

Journal:

Trends in Molecular Medicine

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

47

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF23, Klotho and Vitamin D Interactions:

Year:

2012

Language:

english

File:

PDF, 255 KB

english, 2012

48

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || FGF23 as a Novel Therapeutic Target

Year:

2012

Language:

english

File:

PDF, 158 KB

english, 2012

49

[Advances in Experimental Medicine and Biology] Endocrine FGFs and Klothos Volume 728 || Regulation of Ion Channels by Secreted Klotho

Year:

2012

Language:

english

File:

PDF, 176 KB

english, 2012

50

12 Loss of Gastric Interstitial Cells of Cajal and Impaired Electrical Pacemaking in Klotho Mice, an Animal Model of Aging

Ferenc Izbeki, Andrea Lorincz, David T. Asuzu, Laura Popko, David L. Young, Michael R. Bardsley, Yujiro Hayashi, Makoto Kuro-o, Gianrico Farrugia, Tamas Ordog

Journal:

Gastroenterology

Year:

2010

Language:

english

File:

PDF, 74 KB

english, 2010